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human kidney single-cell transcriptome database (scrna-seq)  (Broad Institute Inc)

 
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    Broad Institute Inc human kidney single-cell transcriptome database (scrna-seq)
    Expression of genes associated with SARS-CoV-2 entry in single-cell <t>transcriptome</t> sequencing database. a UMAP visualization displaying major cell clusters (22,268 single cells). b Dot plot of LRP2 and CUBN (marker genes of PT cells), ACE2, TMPRSS2, and SLC6A19; dot size represents the fraction of cells expressing a cell type, and color intensity binned count-based expression level amongst expressing cells. c UMAP projection, points colored by detection of ACE2 (left), TMPRSS2 (middle), and SLC6A19 (right). Blue, RNA positive; gray, RNA negative. d Volcano plot displaying differential expression of genes between ACE2+ and ACE2– PT cells. Red, up-regulated genes; blue, down-regulated genes. e Bar plot presenting significantly enriched GO terms obtained from GO enrichment analysis performed with differential expression of genes between ACE2+ and ACE2– PT cells.
    Human Kidney Single Cell Transcriptome Database (Scrna Seq), supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/single+cell+transcriptome+databases/human+kidney+single+cell+transcriptome+database++scrna+seq+/pmc07316659-76-3-11
    Average 90 stars, based on 1 article reviews
    human kidney single-cell transcriptome database (scrna-seq) - by Bioz Stars, 2026-10
    90/100 stars

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    1) Product Images from "Localization of Cell Receptor-Related Genes of SARS-CoV-2 in the Kidney through Single-Cell Transcriptome Analysis"

    Article Title: Localization of Cell Receptor-Related Genes of SARS-CoV-2 in the Kidney through Single-Cell Transcriptome Analysis

    Journal: Kidney Diseases

    doi: 10.1159/000508162

    Expression of genes associated with SARS-CoV-2 entry in single-cell transcriptome sequencing database. a UMAP visualization displaying major cell clusters (22,268 single cells). b Dot plot of LRP2 and CUBN (marker genes of PT cells), ACE2, TMPRSS2, and SLC6A19; dot size represents the fraction of cells expressing a cell type, and color intensity binned count-based expression level amongst expressing cells. c UMAP projection, points colored by detection of ACE2 (left), TMPRSS2 (middle), and SLC6A19 (right). Blue, RNA positive; gray, RNA negative. d Volcano plot displaying differential expression of genes between ACE2+ and ACE2– PT cells. Red, up-regulated genes; blue, down-regulated genes. e Bar plot presenting significantly enriched GO terms obtained from GO enrichment analysis performed with differential expression of genes between ACE2+ and ACE2– PT cells.
    Figure Legend Snippet: Expression of genes associated with SARS-CoV-2 entry in single-cell transcriptome sequencing database. a UMAP visualization displaying major cell clusters (22,268 single cells). b Dot plot of LRP2 and CUBN (marker genes of PT cells), ACE2, TMPRSS2, and SLC6A19; dot size represents the fraction of cells expressing a cell type, and color intensity binned count-based expression level amongst expressing cells. c UMAP projection, points colored by detection of ACE2 (left), TMPRSS2 (middle), and SLC6A19 (right). Blue, RNA positive; gray, RNA negative. d Volcano plot displaying differential expression of genes between ACE2+ and ACE2– PT cells. Red, up-regulated genes; blue, down-regulated genes. e Bar plot presenting significantly enriched GO terms obtained from GO enrichment analysis performed with differential expression of genes between ACE2+ and ACE2– PT cells.

    Techniques Used: Expressing, Sequencing, Marker, Quantitative Proteomics

    Expression of genes associated with SARS-CoV-2 entry in single-nuclear transcriptome. a Dot plot of LRP2 and CUBN (marker genes of PT cells), ACE2, TMPRSS2, and SLC6A19; dot size represents the fraction of cells expressing each cell type, and color intensity binned count-based expression level amongst expressing cells. b Bar plot presenting significantly enriched GO terms obtained from GO enrichment analysis performed with differential expression of genes between ACE2+ and ACE2– PT cells. c Violin plot showing ACE2, SLC6A19, and TMPRSS2 expression distribution among different cell clusters.
    Figure Legend Snippet: Expression of genes associated with SARS-CoV-2 entry in single-nuclear transcriptome. a Dot plot of LRP2 and CUBN (marker genes of PT cells), ACE2, TMPRSS2, and SLC6A19; dot size represents the fraction of cells expressing each cell type, and color intensity binned count-based expression level amongst expressing cells. b Bar plot presenting significantly enriched GO terms obtained from GO enrichment analysis performed with differential expression of genes between ACE2+ and ACE2– PT cells. c Violin plot showing ACE2, SLC6A19, and TMPRSS2 expression distribution among different cell clusters.

    Techniques Used: Expressing, Marker, Quantitative Proteomics

    Expression of genes associated with SARS-CoV-2 entry in a single-cell transcriptome sequencing database of Asians. a Dot plot of LRP2 and CUBN (marker genes of PT cells), ACE2, TMPRSS2, and SLC6A19; dot size represents the fraction of cells expressing each cell type, and color intensity binned count-based expression level amongst expressing cells. b Bar plot presenting significantly enriched GO terms obtained from GO enrichment analysis performed with differential expression of genes between ACE2+ and ACE2– PT cells.
    Figure Legend Snippet: Expression of genes associated with SARS-CoV-2 entry in a single-cell transcriptome sequencing database of Asians. a Dot plot of LRP2 and CUBN (marker genes of PT cells), ACE2, TMPRSS2, and SLC6A19; dot size represents the fraction of cells expressing each cell type, and color intensity binned count-based expression level amongst expressing cells. b Bar plot presenting significantly enriched GO terms obtained from GO enrichment analysis performed with differential expression of genes between ACE2+ and ACE2– PT cells.

    Techniques Used: Expressing, Sequencing, Marker, Quantitative Proteomics

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    Article Snippet: .. To understand in which retinal cell types the 52 DEGs are expressed, we queried several retina expression databases, including single cell transcriptome databases (Macosko et al., 2015; Shekhar et al., 2016; Siegert et al., 2009, 2012; Woods et al., 2018), as well as PubMed (htt ps://pubmed.ncbi.nlm.nih.gov/) and search tools such as “Google” (https://www.google.com/). ..

    Single Cell:

    Article Title: Shedding light on myopia by studying complete congenital stationary night blindness.
    Article Snippet: .. To understand in which retinal cell types the 52 DEGs are expressed, we queried several retina expression databases, including single cell transcriptome databases (Macosko et al., 2015; Shekhar et al., 2016; Siegert et al., 2009, 2012; Woods et al., 2018), as well as PubMed (htt ps://pubmed.ncbi.nlm.nih.gov/) and search tools such as “Google” (https://www.google.com/). ..



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    Expression of genes associated with SARS-CoV-2 entry in single-cell <t>transcriptome</t> sequencing database. a UMAP visualization displaying major cell clusters (22,268 single cells). b Dot plot of LRP2 and CUBN (marker genes of PT cells), ACE2, TMPRSS2, and SLC6A19; dot size represents the fraction of cells expressing a cell type, and color intensity binned count-based expression level amongst expressing cells. c UMAP projection, points colored by detection of ACE2 (left), TMPRSS2 (middle), and SLC6A19 (right). Blue, RNA positive; gray, RNA negative. d Volcano plot displaying differential expression of genes between ACE2+ and ACE2– PT cells. Red, up-regulated genes; blue, down-regulated genes. e Bar plot presenting significantly enriched GO terms obtained from GO enrichment analysis performed with differential expression of genes between ACE2+ and ACE2– PT cells.
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    Image Search Results


    Expression of genes associated with SARS-CoV-2 entry in single-cell transcriptome sequencing database. a UMAP visualization displaying major cell clusters (22,268 single cells). b Dot plot of LRP2 and CUBN (marker genes of PT cells), ACE2, TMPRSS2, and SLC6A19; dot size represents the fraction of cells expressing a cell type, and color intensity binned count-based expression level amongst expressing cells. c UMAP projection, points colored by detection of ACE2 (left), TMPRSS2 (middle), and SLC6A19 (right). Blue, RNA positive; gray, RNA negative. d Volcano plot displaying differential expression of genes between ACE2+ and ACE2– PT cells. Red, up-regulated genes; blue, down-regulated genes. e Bar plot presenting significantly enriched GO terms obtained from GO enrichment analysis performed with differential expression of genes between ACE2+ and ACE2– PT cells.

    Journal: Kidney Diseases

    Article Title: Localization of Cell Receptor-Related Genes of SARS-CoV-2 in the Kidney through Single-Cell Transcriptome Analysis

    doi: 10.1159/000508162

    Figure Lengend Snippet: Expression of genes associated with SARS-CoV-2 entry in single-cell transcriptome sequencing database. a UMAP visualization displaying major cell clusters (22,268 single cells). b Dot plot of LRP2 and CUBN (marker genes of PT cells), ACE2, TMPRSS2, and SLC6A19; dot size represents the fraction of cells expressing a cell type, and color intensity binned count-based expression level amongst expressing cells. c UMAP projection, points colored by detection of ACE2 (left), TMPRSS2 (middle), and SLC6A19 (right). Blue, RNA positive; gray, RNA negative. d Volcano plot displaying differential expression of genes between ACE2+ and ACE2– PT cells. Red, up-regulated genes; blue, down-regulated genes. e Bar plot presenting significantly enriched GO terms obtained from GO enrichment analysis performed with differential expression of genes between ACE2+ and ACE2– PT cells.

    Article Snippet: In the latest human kidney single-cell transcriptome database (scRNA-seq) from the Broad Institute and the University of Michigan [ ], we found significant expression of ACE2 in PT cells, glomerular parietal epithelial cells, and descending thin limb cells (Fig. ; online suppl.

    Techniques: Expressing, Sequencing, Marker, Quantitative Proteomics

    Expression of genes associated with SARS-CoV-2 entry in single-nuclear transcriptome. a Dot plot of LRP2 and CUBN (marker genes of PT cells), ACE2, TMPRSS2, and SLC6A19; dot size represents the fraction of cells expressing each cell type, and color intensity binned count-based expression level amongst expressing cells. b Bar plot presenting significantly enriched GO terms obtained from GO enrichment analysis performed with differential expression of genes between ACE2+ and ACE2– PT cells. c Violin plot showing ACE2, SLC6A19, and TMPRSS2 expression distribution among different cell clusters.

    Journal: Kidney Diseases

    Article Title: Localization of Cell Receptor-Related Genes of SARS-CoV-2 in the Kidney through Single-Cell Transcriptome Analysis

    doi: 10.1159/000508162

    Figure Lengend Snippet: Expression of genes associated with SARS-CoV-2 entry in single-nuclear transcriptome. a Dot plot of LRP2 and CUBN (marker genes of PT cells), ACE2, TMPRSS2, and SLC6A19; dot size represents the fraction of cells expressing each cell type, and color intensity binned count-based expression level amongst expressing cells. b Bar plot presenting significantly enriched GO terms obtained from GO enrichment analysis performed with differential expression of genes between ACE2+ and ACE2– PT cells. c Violin plot showing ACE2, SLC6A19, and TMPRSS2 expression distribution among different cell clusters.

    Article Snippet: In the latest human kidney single-cell transcriptome database (scRNA-seq) from the Broad Institute and the University of Michigan [ ], we found significant expression of ACE2 in PT cells, glomerular parietal epithelial cells, and descending thin limb cells (Fig. ; online suppl.

    Techniques: Expressing, Marker, Quantitative Proteomics

    Expression of genes associated with SARS-CoV-2 entry in a single-cell transcriptome sequencing database of Asians. a Dot plot of LRP2 and CUBN (marker genes of PT cells), ACE2, TMPRSS2, and SLC6A19; dot size represents the fraction of cells expressing each cell type, and color intensity binned count-based expression level amongst expressing cells. b Bar plot presenting significantly enriched GO terms obtained from GO enrichment analysis performed with differential expression of genes between ACE2+ and ACE2– PT cells.

    Journal: Kidney Diseases

    Article Title: Localization of Cell Receptor-Related Genes of SARS-CoV-2 in the Kidney through Single-Cell Transcriptome Analysis

    doi: 10.1159/000508162

    Figure Lengend Snippet: Expression of genes associated with SARS-CoV-2 entry in a single-cell transcriptome sequencing database of Asians. a Dot plot of LRP2 and CUBN (marker genes of PT cells), ACE2, TMPRSS2, and SLC6A19; dot size represents the fraction of cells expressing each cell type, and color intensity binned count-based expression level amongst expressing cells. b Bar plot presenting significantly enriched GO terms obtained from GO enrichment analysis performed with differential expression of genes between ACE2+ and ACE2– PT cells.

    Article Snippet: In the latest human kidney single-cell transcriptome database (scRNA-seq) from the Broad Institute and the University of Michigan [ ], we found significant expression of ACE2 in PT cells, glomerular parietal epithelial cells, and descending thin limb cells (Fig. ; online suppl.

    Techniques: Expressing, Sequencing, Marker, Quantitative Proteomics